Maximum dose of valocardine. Valokordin - composition, instructions for use, indications, side effects, analogues and price

Valokordin: instructions for use and reviews

Latin name: Valocordin.

ATX code: n05cb02

Active substance: Phenobarbital + ethylbromisovalerianate + mint oil + hop oil (PhenobarBital + Ethylbromisovalerinate + Menthae Piperitae Oleum + Humuli Lupuli Oleum)

Manufacturer: Krewel Meuselbach, GmbH (Germany)

Actualization of the description and photo: 16.08.2019

Valokordin is a combined preparation with sedative, sleeping pills and antispasmodic effect.

Release form and composition

Valvekordin is produced in the form of droplets for intake (transparent colorless liquid with fragrant odor), 20 ml and 50 ml in dark glass flocks-droppers, 1 bottle in a cardboard pack.

The composition of 1 ml of drops includes active substances:

  • Ethylbromisovalerianate - 18.4 mg;
  • Phenobarbital - 18.4 mg.

Auxiliary components that are part of the drug: Hop oil - 0.18 mg; Mint oil - 1.29 mg; 96% ethanol - 469.75 mg; Purified water - 411.97 mg.

Pharmacological properties

Pharmacodynamics

Valoccoordin is a combined drug, the therapeutic effect of which is due to the pharmacological properties of components included in its composition.

Ethylbromisovalerianate has sedative, antispasmodic and sleeping pills.

Phenobarbital has a sedative and soft impact effect, reducing the excitation of the central nervous system and facilitating the offensive of natural sleep.

Indications for use

According to the instructions, the valve edge is prescribed under the following diseases / states:

  • Functional disorders of the cardiovascular system, including cardialgia and sinus tachycardia;
  • Insomnia (hurt);
  • Neurosis, accompanied by anxiety, irritability and fear;
  • The state of excitation with severe vegetative reactions.

Contraindications

  • Pronounced disorders of the liver and / or kidney function;
  • Pregnancy and lactation period;
  • Children's age up to 18 years;
  • Increased sensitivity to the components of the drug.

With caution, droplets are used in cranial injuries, liver diseases, alcoholism, brain diseases (due to ethanol included in the preparation).

Instructions for the use of Wolkordin: Method and Dosage

Drops of valocardine are taken inside with a small amount of liquid before meals.

The dosage and duration of the use of the doctor installs individually.

Usually adults are prescribed 3 times a day at 15-20 drops. With fallout disappearance, a dose increases to 30 drops.

Children, taking into account the clinical picture of the disease, on average, are prescribed 1 drop for the year of life.

Side effects

Valokordin even with prolonged use, as a rule, is well tolerated. Sometimes in the daytime there may be light dizziness and drowsiness.

Long-term use of large doses can lead to the development of chronic poisoning by bromine, manifested as:

  • Rhinitis;
  • Violation of coordination of movements;
  • Depressive mood;
  • Conjunctivitis;
  • Apathy;
  • Hemorrhagic diathesis.

In some cases, at elevated sensitivity, skin reactions are possible.

If you have any uncharacteristic effects not specified in the instructions, you should contact your doctor.

Overdose may occur:

  • Lightweight and medium-heavy inxication - dizziness, drowsiness, psychomotor disorders;
  • Heavy cases - tachycardia, vascular collapse, coma, respiratory impairment, reduction of blood pressure, reduction of peripheral reflexes.

For treatment, it is shown to wash the stomach and receiving activated carbon. When symptoms appear an overdose, it is recommended to urgently consult a doctor.

Overdose

Symptoms of medium and light intoxication: dizziness, psychomotor disorders, drowsiness.

In severe cases of overdose, blood pressure is reduced, breathing disrupts, peripheral reflexes are reduced. It is possible to develop a vascular collapse, tachycardia, coma.

Treatment: stomach wash, activated carbon. You need to contact your doctor.

special instructions

If necessary, the appointment of Walocordin during lactation, breastfeeding must be stopped.

Because of the phenobarbital, which has a sleeping pills, and ethanol, which contains 469 mg in 30 drops (maximum one-time dose), the drug can weaken the ability of the patient to respond quickly in certain situations, for example, when servicing cars or while staying outside. This is especially expressed in simultaneous admission with alcohol.

In the case of long-term use of Valocardin:

  • Drug Development Development;
  • Accumulation in the body of bromine with subsequent poisoning.

Application during pregnancy and lactation

It is forbidden to use drops of valocardine during periods of pregnancy and lactation.

Childcare

It is forbidden to use the preparation for the treatment of patients under the age of 18 years.

With violations of the kidney function

It is forbidden to use valocardine with pronounced renal impairments.

When violations of the liver function

It is forbidden to use valocardine with privileges of the liver function. With liver diseases, the drug should be taken with caution.

Medicinal interaction

With simultaneous reception of sedatives, an increase in effect is observed.

Sharing with tranquilizers and neuroleptics amplifies, and with stimulants of the central nervous system - weakens the action of each of the components of the drug.

Alcohol can increase the toxicity of the Valocardine and enhances its effect.

The phenobarbital contained in the preparation is capable of induced by microsomal liver enzymes. As a result, it is undesirable to use its simultaneous use with metabolizing in the liver drugs, because Their concentration, and, accordingly, efficiency, as a result of more accelerated metabolism, will decrease (antibiotics, indirect anticoagulants, sulfonamides).

Also, phenobarbital weakens the effect of griseofullvin, glucocorticosteroids, Cumarine derivatives and oral contraceptives.

Analogs

Analogues of the Valocardine are: Barbal, Darvipol, Valecard, Korvalol, Korwaladin, Corvaltab, Corvalkaps.

Terms and conditions of storage

Store in the place protected from light, inaccessible to children at a temperature of 15-25 ° C.

Shelf life - 5 years.

The combined medicine with sedative and antispasmodic action is Valokordin. Instructions for use reports that drops, pills. Swiming doxillamine also have a sleeping pill effect. The medication helps in neurosis therapy, insomnia, tachycardia.

Release form and composition

The drug Valokordin is produced in the form of droplets for intake in bottles-drops from dark glass of 20 in a cardboard pack. In the bottle, a transparent liquid with a pronounced mint smell.

The main active ingredients of the drops are phenobarbital and ethylbromisovalerianate in equal amounts - 18.4 mg. In addition, as part of the drug, the auxiliary components - ethanol 96%, peppermint oil, hop oil, purified water.

Tablets are also produced by the pills of 15 mg of Valokordin doxylamine containing doxylamine succinate and auxiliary substances.

pharmachologic effect

The therapeutic effect of the use of valocardine is due to the pharmacological properties of its components. Phenobarbital has a vasodilant (vasodilative), sedative (soothing) action and soft sleeping pills.

Under its influence, the excitation of the central nervous system is reduced, and optimal conditions for natural sleep are created. Ethylbromisovalerianate also has a sedative and sleeping pills. This component has an antispasmodic effect. Mint oil has reflex antispasmodic and vasodilatory activity.

Indications for use

What helps Valokordin? Drops are prescribed with sinus tachycardia, cardialgia and other forms of functional disorders of the cardiovascular system.

The drug is effective in insomnia, neurosis, irritability, alarming, anxiety, anxiety, which is accompanied by pronounced reactions from the vegetative nervous system.

Instructions for use

Drops of valocardine are taken inward, to meals, with a small amount of liquid. How many drops need to achieve the therapeutic effect? The dosage is established individually. Adults are prescribed usually 15-20 drops 3 times a day. With a disturbed dose, you can increase to 30 drops.

Children are prescribed at the rate of 1 drop for the year of the child's life and, depending on the clinical picture of the disease. The duration of the use of the drug is established individually by the doctor.

Sympuchi pills

Take inside. Adults with insomnia, sleep disorders - 15-25 mg 15-30 minutes before sleep. In allergic reactions - in doses up to 25 mg every 4-6 hours. Children aged 6-12 years - at 6.25-12.5 mg, if necessary, every 4-6 hours. Maximum daily dose for adults - 150 mg.

See also: How to make a sedative analogue.

Contraindications

  • Increased sensitivity to the components of the drug;
  • Pronounced disorders of the liver and / or kidney function;
  • Children's age up to 18 years;
  • Pregnancy and lactation period.

With caution, droplets are used in cranial injuries, liver diseases, alcoholism, brain diseases (due to ethanol included in the preparation).

Sideflines

Even the long-term use of Valocard is usually transferred well. When receiving the testimony of Walocordinity in the daytime, there is sometimes light dizziness and drowsiness. However, the long-term use of the medication in doses, which exceed the recommended in the instructions, may appear symptoms of bromine poisoning as:

  • Rhinitis;
  • Hemorrhagic diathesis;
  • Disorders coordination movements;
  • Depressive mood;
  • Conjunctivitis;
  • Apathy.

Children, during pregnancy and breastfeeding

During pregnancy, the preparation of the drug is the city of contraindicated. If it is necessary to appoint the drug during the lactation period, it is necessary to resolve the issue of cessation of breastfeeding.

Application in children

Children are prescribed at the rate of 1 drop for the year of the child's life and, depending on the clinical picture of the disease.

special instructions

In case of diseases of the liver and brain, alcoholism and crank and brain injuries, the use of valocardine should be extremely careful because the preparation contains ethanol. If there is a need for prescribing the drug during lactation, breastfeeding for the treatment stops.

Even with proper use, the Valvekordin can significantly affect the speed of the patient's reaction, so in treatment it is necessary to show special care - to refrain from exits to the street, managing vehicles and mechanisms and other actions requiring increased attention and speed of motor reactions.

Medicinal interaction

In combination with sedatives, an increase in effect is marked. The effect of tranquilizers and neuroleptics is enhanced by simultaneously receiving with a foamordin, and the CNS stimulants lose their effectiveness.

Analogs of drugs Valokordin

According to the structure, the analog is determined - Kalvadin.

Sedable tools include analogues:

  1. Voserdin.
  2. Valerian drops with adormizid and sodium bromide.
  3. Bellataminal.
  4. Muscovy balm.
  5. Hopnation hop.
  6. Valemidine.
  7. Cravelon.
  8. Phyluors.
  9. Sedal fee number 2.
  10. Sanason Lek.
  11. Klosterfrau Melusan.
  12. Valerian drops.
  13. Landshevo-dyeing drops.
  14. Phytosedan number 3.
  15. Valeodicramen.
  16. Sedophlor.
  17. Novo passite.
  18. Snend Forte.
  19. Barbal.
  20. Valerian.
  21. Corwalola Mff.
  22. Song Knight.
  23. Phytosedan number 2.
  24. Doppelgers Melissa.
  25. Soothing collection number 3.
  26. Motherwort.
  27. Glycine.
  28. Carniland.
  29. Hop extract liquid.
  30. Adonis Brom.
  31. Doppelgers Vitalotonik.
  32. Klofit.
  33. Corvalol.
  34. Bromenval.
  35. Passif.
  36. Negrustine.
  37. Slipex
  38. Success.
  39. Soothing collection number 2.
  40. Lotosonic.
  41. St. John's wort
  42. Phyto Novo Sed.

Vacation conditions and price

The average cost of Valokordin-doxylamine (drops of 25 mg / ml, 20 ml) in Moscow is 240 rubles. Droplets are released in pharmacies without a doctor's prescription.

The shelf life of the drug is 5 years from the date of the production date, which is indicated on the package. Upon expiration of this period, the drug cannot be taken inside. The drug Valokordin instructions for use proposes to store in an inaccessible place at a temperature of no more than 15 degrees (preferably in the refrigerator).

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Valokordin- a combined sedative drug, the therapeutic effect of which is due to the pharmacological properties of the components included in its composition. Phenobarbital has a sedative and mild sleeping pills.
It helps to reduce the excitation of the central nervous system and facilitates the offensive of natural sleep. Ethylbromisovalerianate has a sedative, sleeping pills and antispasmodic effect.

Indications for use:
Drops Valokordinit is recommended to take with functional disorders of the cardiovascular system (including cardialgy, sinus tachycardia); neurosis, accompanied by irritability, anxiety, fear; insomnia (falling asleep difficulties); The states of excitation, accompanied by severe vegetative reactions.

Mode of application:
Valokordintake inside, before meals, with a small amount of fluid.
The dose is established individually.
Adults are usually prescribed 15-20 drops 3 times a day.
With a disturbed dose, you can increase to 30 drops.
The duration of the use of the drug is established individually by the doctor.

Side effects:
ValokordinAs a rule, it is well tolerated even with long-term use. In some cases, in daytime hours there may be drowsiness and light dizziness.
With long-term use of large doses, the development of chronic poisoning by bromine, the manifestations of which are: depressive mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, disruption of coordination of movements.
Rarely, at elevated sensitivity, skin reactions may occur.
With the manifestation of any side (unusual) effects that are not reflected in the instructions, it is necessary to inform about them at the attending physician.

Contraindications:
Contraindications for the use of the drug Valokordinare: increased sensitivity to any of the components of the drug; pronounced disorders of the kidney function and / or liver; Pregnancy, lactation period, child age up to 18 years old.
With caution: liver disease, alcoholism, brain injury, brain disease. The drug contains ethanol.

Pregnancy:
During pregnancy, take drops Valokordincontraindicated.

Interaction with other drugs:
With simultaneous use Valokordinawith sedative means - enhancing effect. Simultaneous use with neuroleptics and tranquilizers increases, and with stimulants of the central nervous system - weakens the action of each of the components of the drug. Alcohol enhances the effects of Walocordin® and can increase its toxicity. The presence of phenobarbital microordinal enzymes can induce the microsomal liver enzymes, and this makes it undesirable to its simultaneous use with drugs that are metabolized in the liver, since their concentration and, accordingly, the effectiveness will be changed as a result of more accelerated metabolism (indirect anticoagulants, antibiotics, sulfonamides and antibiotics dr.)
The phenobarbital weakens the effect of Kumarin derivatives, glucocorticosteroids, griseofullvin, oral contraceptive means.

Overdose:
With mild and medium-heating inxication, drowsiness, dizziness, psychomotor disorders are observed.
In severe cases - coma, decrease in blood pressure, respiratory disorder, tachycardia, vascular collapse, reduction of peripheral reflexes.
Treatment: Rinse the stomach, take activated coal and urgently call a doctor.

Storage conditions:
Store in the light-protected place at a temperature of from 15 ° C to 25 ° C.
Keep out of the reach of children.

Release form:
Valokordin - drops for intake.
20 ml, 50 ml in brown glass bottle with a dropper.

Structure:
1 ml of preparation Valokordincontains active substances: phenobarbital - 18.40 mg, ethylbromisovalerianate - 18.40 mg.
Auxiliary substances: Mint oil - 1.29 mg, hop oil - 0.18 mg, ethanol 96% - 469.75 mg, purified water - 411.97 mg.

Additionally:
If necessary, prescribe a drug Valokordinduring the lactation, it is necessary to resolve the issue of cessation of breastfeeding.
The drug contains 55 volume% ethanol (the absolute content of ethanol in the maximum single dose (30 drops) is 0.469 grams) and phenobarbital, therefore Valokordin® even with proper use can weaken the ability of patients to respond quickly in certain situations, such as, for example, while staying outside or when servicing machines. This is especially expressed in the simultaneous intake of alcohol.
With prolonged use of the drug, the formation of drug addiction is possible; It is possible to accumulate bromine in the body and the development of poisoning them.

Seding drug

Active substances

Release form, composition and packaging

Drops for reception inside In the form of a transparent, colorless liquid with fragrant smell.

Auxiliary substances: Mint oil - 1.29 mg, Khmelev oil - 0.18 mg, ethanol 96% - 469.75 mg, purified water - 411.97 mg.

20 ml - Dark glass droppers (1) - Cardboard packs.
50 ml - Drop Glass Drops (1) - Putures Cardboard.

pharmachologic effect

Valokordin is a combined drug, the therapeutic effect of which is due to the pharmacological properties of the components included in its composition.

Phenobarbital It has a sedative and mild sleeping pills. It helps to reduce the excitation of the CNS and facilitates the offensive of natural sleep.

Ethylbromisovalerianateit has a sedative, sleeping pills and antispasmodic effect.

Indications

Contraindications

  • increased sensitivity to any of the components of the drug;
  • pronounced disorders of the kidney function and / or liver;
  • lactation period;
  • children's age up to 18 years.

Carefully

Liver diseases, alcoholism, cranial and brain injury, brain disease, because The drug contains ethanol.

Dosage

Valokordin takes inside, before meals, with a small amount of liquid. The dose is established individually.

Adults Appointed usually 15-20 drops 3 times / day.

For disappeared Dose can be increased to 30 drops.

The duration of the use of the drug is established individually by the doctor.

Side effects

Valokordin, as a rule, is well tolerated even with long-term use.

In some cases: In daytime, drowsiness can be observed and easy.

With long-term use of large doses It is possible to develop chronic poisoning by bromine, whose manifestations are: depressive mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, violation of coordination of movements.

Rarely, with high sensitivity:skin reactions.

With the manifestation of any side (unusual) effects that are not reflected in the instructions, it is necessary to inform about them at the attending physician.

Overdose

Symptoms: With mild and medium-heating inxication, drowsiness, dizziness, psychomotor disorders are observed. In severe cases - coma, decreased blood pressure, respiratory disorder, tachycardia, vascular collapse, decrease in peripheral reflexes.

Treatment:washing the stomach, receiving activated carbon. You should urgently call a doctor.

Medicinal interaction

With the simultaneous use of the preparation of valocardin with sedatives, an increase in effect is marked.

Simultaneous use with neuroleptics and tranquilizers amplifies, and with ZNS stimulants - weakens the action of each of the components of the drug.

Alcohol enhances the effects of the drug of the Valokordin and can increase its toxicity.

The presence of phenobarbital enzymes in the preparation of the drug can induce the liver enzymes, and this makes it unwanted its simultaneous use with drugs that are metabolized in the liver, since their concentration, and accordingly, efficiency will decrease as a result of more accelerated metabolism (indirect, antibiotics, sulfanimides, etc. ).

Phenobarbital weakens the effect of Kumarin derivatives, GKS, Griece Fullwine, oral contraceptives.

special instructions

The drug contains 55 volumetric% ethanol (the absolute content of ethanol in the maximum single dose (30 drops) is 0.469 g) and phenobarbital, therefore the valve edge even with proper use can weaken the ability of patients to respond quickly in certain situations, such as when staying on the street or When servicing machines. This is especially expressed in the simultaneous intake of alcohol.

With prolonged use of the drug, the formation of drug addiction is possible; It is possible to accumulate bromine in the body and the development of them.

The combined drug whose action is due to the properties of the substances included in its composition. It has a sedative and antispasmodic effect. It facilitates the offensive of natural sleep.

Ethyl ester of α-bromoisovalerian acid has a sedative (similar to the effect of valerian) and antispasmodic effect.

Phenobarbital enhances the sedative effect of other components and has a slight hypotensive effect.

The pepper mint oil has a reflex vazodilative and antispasmodic effect.

Form release

Drops for intakes in the form of a transparent colorless liquid with fragrant odor.

Auxiliary substances: Mint oil - 1.29 mg, Khmelev oil - 0.18 mg, ethanol 96% - 469.75 mg, purified water - 411.97 mg.

20 ml - Dark Glass Drops (1) - Putures Cardboard.
50 ml - Dark Glass Drops (1) - Putures Cardboard.

Dosage

Inside, before taking food, 15-30 cap, pre-soluble in a small amount (30-50 ml) of water, 2-3 times a day. One-time dose if necessary (for example, with tachycardia) can be increased to 40-50 cap.

Children - 3-15 Cap / day (depending on the age and clinical picture of the disease).

The duration of the use of the drug is established by the doctor individually.

Side effects

Drowsiness, dizziness, reduction of the ability to concentrate attention, allergic reactions.

With long-term reception - chronic bromine poisoning (depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, movement coordination disorders); Drug addiction.

Indications

As a sedative and vasodilator:

  • insomnia (falling off);
  • cardialia;
  • sinus tachycardia;
  • neurotic states;
  • vegetative lability;
  • irritability;
  • hypochondriac syndrome;
  • arterial hypertension (early stages).

As a spasmolytic agent:

  • spasm muscles of the gastrointestinal bodies (intestinal and bile colic).

Contraindications

  • hypersensitivity;
  • heavy hepatic and / or renal failure.

Features of application

Application in pregnancy and breastfeeding

C care: pregnancy, lactation period.

Application with violations of liver function

The use of the drug is contraindicated with severe liver failure.

Application with violations of the kidney function

The use of the drug is contraindicated in severe renal failure.

Application in children

Application is possible according to the dosing mode.

special instructions

Impact on the ability to driving vehicles and control mechanisms

During the period of treatment, care must be taken when driving vehicles and occupation by other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.